Although the opiate receptor depends on G protein coupling for signal transduction, this receptor was observed to make the most of arrestin activation for internalization in the receptor. If not, the receptor promoted no other… Read More
Conolidine’s analgesic results stem from its interaction with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors while in the central nervous technique, conolidine modulates alternate molecular t… Read More
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